This chapter examines the role of work, particularly manual work, in health decline with age in the U.S. using self-reported health status (SRHS) data from the National Health Interview Survey (NHIS). The findings suggests that work, especially low-paid or manual work, exacts a price in terms of health, as may the consumption patterns of poorer people, in terms of tobacco use, obesity, and lack of exercise. The results also indicates that both income and education have independent protective effects on health for those who are in work and these effects are reduced but not eliminated by controlling for occupation.