The continuing global decline of large carnivores today has catalyzed great interest in reintroduction with the dual goal of restoring populations and reestablishing ecologically important relationships with other species. The repatriation of predators like wolves and bears to their native ecosystems will always be an emotionally charged and culturally disruptive issue. Humans who incur few if any burdens associated with carnivores generally favor restoration; those living rurally and in closer proximity have greater antipathy. In the American West, carnivore repatriation has been especially divisive. This chapter asks: Can prey species adjust to their presence? Indeed, can people?